High-density lipoprotein High-density. The relationship between HDL- , LDL- , liposomes- free cholesterol, biliary cholesterol and bile salts in the rat. Liposomes were used for comparison because they are assimilated by hepatocytes, but are not recognized by specific receptors. HDL isolated from rat sera were labeled with . The peaks of radioactivity appeared in bile 3. HDL or liposome injection and after 2. LDL injection. The kinetic behavior of the cholesterol carried by the liposomes was quite similar to that of cholesterol carried by HDL. Cholesterol carried by HDL was metabolized in bile salts faster than that carried by LDL: cholesterol- HDL or cholesterol- liposomes contributed to the same extent to the secretion of bile cholesterol (1. LDL (2. 0% of the injected dose). However, the main part of . Thus, cholesterol from an exogenous source seemed to be used mainly as a substrate for bile salts. Our study revealed a difference between the hepatic metabolism of HDL, liposomes and LDL in the rat: the kinetic difference between the secretions of the radioactive compounds in bile may be explained by differences in assimilation, intracellular pathways or bile secretion. Relation of Diet to High-Density-Lipoprotein. Including fish in your diet can. Low-density lipoprotein (LDL) cholesterol is considered . The test for low-density lipoprotein cholesterol. HDL cholesterol (HDL-C. Cholesterol Lipoproteins and Cholesterol. Learn how to improve your heart health by lowering LDL and.
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